解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Chemical and microscopic features of wood decay by the basidiomycete Coriolopsis occidentalis are described. The fungus was grown on blocks of poplar, oak, and fir wood and caused significant mass, lignin, and saccharide losses in all kinds of wood. Poplar wood was particularly strongly affected. Twelve weeks after in...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02814527
更新日期:1994-01-01 00:00:00
abstract::We constructed a SmaI genomic library of Cellulomonas biazotea DNA in E. coli and in the S. cerevisiae shuttle vector, YEP 24. Three clone were identified that conferred the ability for E. coli or S. cerevisiae transformants to produce carboxymethylcellulase (CMCase). Cells transformed with these clones were compared ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02814307
更新日期:1994-01-01 00:00:00
abstract::Virulence factors were compared in 15 Aeromonas spp. isolated from faeces of patients with Aeromonas-associated gastroenteritis and in 81 strains isolated from food. Strains from food did not show differences in the distribution of virulence factors when compared with strains isolated from faeces. However, 88.8% of Ae...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02814323
更新日期:1994-01-01 00:00:00
abstract::Crude lipids isolated from Bacillus firmus, but not from other bacilli, were previously found to induce significant resistance against Listeria monocytogenes infection in mice. In this study, formaldehyde- and heat-killed bacterins of eight Bacillus species and some cellular fractions of B. firmus were prepared and te...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02906811
更新日期:1994-01-01 00:00:00
abstract::The present paper reports a modified method for isolation of lysostaphin--a bacteriolytic agent with specific affinity for staphylococcal cell wall. The proposed purification scheme includes three steps. The first procedure is ultrafiltration through a membrane filter giving a yield of 75.6%. The result of ultrafiltra...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02814386
更新日期:1993-01-01 00:00:00
abstract::Biodegradation of two amphiphilic "soft" antimicrobially active derivatives of lauric (dodecanoic) acid, a quaternary ammonium salt and an amine oxide bearing an amide or ester group, was followed using microorganisms from activated sludge. Primary biodegradation was determined by ion-selective electrodes, total biode...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02814548
更新日期:1993-01-01 00:00:00
abstract::Aliphatic 1,2-alkanolamines inhibited beta-glucanase from Candida utilis. The highest inhibitory effect was observed with 1-dodecylamino-3-chloro-2-propanol (Ki = 1.0 mumol/L) and it was much higher than that of D-glucono-delta-lactone. Simple 1,2-alkanolamines, like 2-aminoethanol or 2-methylaminoethanol, did not exh...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02898763
更新日期:1993-01-01 00:00:00
abstract::Streptomyces cinnamonensis produces a new substance named AIB (for anti-isobutyrate) factor which, on a solid medium, efficiently counteracts toxic concentrations not only of isobutyrate but also of other salts of short-chain monocarboxylic acids. In the present study we demonstrate that the AIB factor activity is wid...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02891697
更新日期:1993-01-01 00:00:00
abstract::Using simultaneous fusion of protoplasts of three strains the auxotrophic K3 killer designated MH1 was prepared at a very low frequency and further employed for the transfer of the K3 killer character into a commercial wine yeast. A novel Saccharomyces Bratislava 1K3 strain with desirable technological and anti-yeast ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02814566
更新日期:1992-01-01 00:00:00
abstract::The rosettes formed by mouse peritoneal macrophages or DCH-5 cells and TNP-erythrocytes coated with anti-TNP antibodies of different isotypes were inhibited to various extent by monosaccharides. The most effective inhibitors were N-acetylglucosamine, glucosamine, mannose and N-acetylneuraminic acid in 1-5 mmol/L conce...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02814584
更新日期:1992-01-01 00:00:00
abstract::Brefeldin A has been recently characterized to act as an inhibitor of intracellular protein export with profound effects on the structure and function of the Golgi apparatus in animal cells. Manifold activities of the antibiotic (under different names) published in the 1960's and 1970's are reviewed: effects on fungal...
journal_title:Folia microbiologica
pub_type: 杂志文章,评审
doi:10.1007/BF02814572
更新日期:1992-01-01 00:00:00
abstract::The mathematical theory of substrate-induced acidification by microorganisms was based on special formulation of mass and charge conservation laws for distinct species. The strength of the theory was tested on the ethanol-induced acidification by Candida utilis in pure water and in phthalate buffer. We showed that the...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02836618
更新日期:1992-01-01 00:00:00
abstract::Lengths of permuted regions in the P22 and L phage genomes were estimated from the relative yields of DNA in many electrophoretic bands obtained using several restriction endonucleases. It was found that 3.6 kb (8.7%) of P22-DNA and 7.2 kb (17.8%) of L-DNA were circularly permuted. In both phages the sequential packag...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02933145
更新日期:1992-01-01 00:00:00
abstract::Structural and functional properties of prokaryotic DNA methyltransferases are summarized. The different aspects of the role of DNA methylation which influences DNA-protein interaction in restriction and modification of DNA and in mismatch repair, DNA replication and gene expression are discussed. ...
journal_title:Folia microbiologica
pub_type: 杂志文章,评审
doi:10.1007/BF02815658
更新日期:1992-01-01 00:00:00
abstract::Some Bacillus subtilis mutants with different levels of homoserine dehydrogenase were described. Strains that do not accumulate methionine have a high homoserine dehydrogenase activity. Low activity was detected in mutants where cell growth was completely inhibited by 0.7 mmol/L methionine. A low concentration of dime...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02884064
更新日期:1991-01-01 00:00:00
abstract::Using mutagenesis with N-methyl-N'-nitro-N-nitrosoguanidine, a number of homoserine auxotrophs have been isolated from a glutamate-producing Arthrobacter globiformis excreting L-lysine in good amounts. For further improvement, mutants resistant to the lysine analog S-(2-aminoethyl)-L-cysteine have been isolated from h...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02935823
更新日期:1991-01-01 00:00:00
abstract::Studies on the production of extracellular cellulase in two aquatic hyphomycetes Lunulospora curvula and Flagellospora penicillioides have shown that several factors such as carbon source, nitrogen source, pH and temperature affect the production of the enzyme. Experiments have shown that carboxymethyl cellulose is th...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02814357
更新日期:1991-01-01 00:00:00
abstract::Submerged cultures of the low-production strain of Tolypocladium inflatum DSM 63544 formed a mixture of cyclosporins (CS) consisting of CS-A, CS-B, "CS-3" and "CS-4". Glucose, sucrose and maltose were highly favored for biomass production but provided a different physiological state necessary for CS biosynthesis. Not ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02884035
更新日期:1991-01-01 00:00:00
abstract::A method is presented for the successful decontamination of sparingly soluble pteridine derivatives by microwave irradiation. The method is nondestructive, rapid and effective in eliminating contamination. ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02814514
更新日期:1991-01-01 00:00:00
abstract::Composition of sterol fractions of nystatin-resistant Candida maltosa strains was determined. Using UV-spectrometry, TLC and GLC-MS it was demonstrated that resistance to nystatin is connected with the composition alterations of yeast cell sterols. Block of different stages of ergosterol biosynthesis was revealed in s...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02814494
更新日期:1991-01-01 00:00:00
abstract::Enzyme synthesis of tryptophan from indole, pyruvate and ammonium salts was studied using Escherichia coli cells exhibiting a significant tryptophanase activity. In addition to the effect of cultivation medium composition and cultivation conditions, factors affecting the course of the conversion were investigated. Pro...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02820485
更新日期:1990-01-01 00:00:00
abstract::The mean lengths of G1, S, G2 and M phases of the cell cycle were determined on the basis of the population distribution of Candida utilis grown in a continuous culture under steady-state conditions by using an original mathematical method. The length of the G2 phase was proportional to that of G1; the length of M was...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02821281
更新日期:1990-01-01 00:00:00
abstract::The temperature dependence of fluorescence anisotropy, lifetime and differential tangent of 1,6-diphenyl-1,3,5-hexatriene (DPH) and its polar trimethylammonium derivative (TMA-DPH) were investigated in cytoplasmic membranes of Bacillus subtilis. The fluorescence parameters were compared in the two types of membranes p...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02821406
更新日期:1990-01-01 00:00:00
abstract::Three methods were used for the isolation of fungi in the present investigation: the dilution-plate method, hair-baiting technique with horse hairs and the "exposed plate" method. Sabouraud's glucose agar at 28 degrees C was also used as isolation medium. 102 species and 2 species varieties belonging to 36 genera were...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02821282
更新日期:1990-01-01 00:00:00
abstract::As phospholipases of mycoplasma species may play a role in the pathogenesis of respiratory tract and urogenital tract diseases Mycoplasma mycoides and Acholeplasma laidlawii were examined as to the production of phospholipase A2 (PLA) and attempts were made to purify and characterize it. Both species produced PLA. The...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02814471
更新日期:1989-01-01 00:00:00
abstract::The antifungal effect of 2-alkylthio-6-amino- and 2-alkylthio-6-formamidobenzothiazoles (22 derivatives in all) on Aspergillus niger and various Candida yeasts was tested. No significant effect was observed with A. niger. With the pathogenic yeast species C. albicans and C. guilliermondii, the most efficient derivativ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02814461
更新日期:1989-01-01 00:00:00
abstract::One hundred clinical isolates of Pseudomonas aeruginosa were checked for their sensitivity towards silver nitrate. Majority of the isolates were resistant at 20 mg/L and the resistance decreased with increasing concentration of silver nitrate, only 5% of the organisms showed resistance above 70 mg/L. These silver-resi...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02820752
更新日期:1989-01-01 00:00:00
abstract::Inducible pigmentation changes were observed in pigmented strains of Brevibacterium sp. M27 and B. flavum treated with N-methyl-N'-nitro-N-nitrosoguanidine. The highest frequency of induction was reached already at a survival of 30-40% with the maximal yield of 6-10%. As compared with the initial yellow colour, three ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02928007
更新日期:1988-01-01 00:00:00
abstract::Different mechanistic models for potassium ion uptake are analyzed by an equilibrium-thermodynamic formalism in terms of their comparative efficiency in setting chemical potential differences of the potassium ion of different magnitudes across the plasma membrane of lower eukaryotic cells. The possible adaptive advant...
journal_title:Folia microbiologica
pub_type: 杂志文章,评审
doi:10.1007/BF02925852
更新日期:1988-01-01 00:00:00
abstract::The validity of the principle of homeoviscous adaptation for Bacillus subtilis was tested by comparing fluorescence anisotropy (1,6-diphenyl-1,3,5-hexatriene) and electron-spin resonance (16-doxylstearate) measurements carried out in isolated plasma membranes and in phospholipid fractions. The physical measurements we...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02925901
更新日期:1988-01-01 00:00:00
abstract::Resistance determinants for HgCl2 and CdCl2 were eliminated along with a number of antibiotic resistance factors from Acinetobacter lwoffi and Micrococcus sp. at 44 degrees C. These organisms were orginally resistant to HgCl2, merbromin, CdCl2, Pb(NO3)2, benzylpenicillin, erythromycin, carbenicillin, tetracycline and ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02925907
更新日期:1988-01-01 00:00:00
abstract::Data on the production of clostridial toxins in dialyzed cultures are summarized. Principal modifications of this cultivation technique suitable for both research and production are shown. If toxins are released from the cells by autolysis (neurotoxins of Clostridium tetani, C. botulinum; lethal factors of C. novyi an...
journal_title:Folia microbiologica
pub_type: 杂志文章,评审
doi:10.1007/BF02928083
更新日期:1988-01-01 00:00:00
abstract::A series of experiments were performed with P. aeruginosa to demonstrate which of the biochemical mechanisms are responsible for the resistance to the beta-lactam antibiotics. The constitutive beta-lactamase was isolated and characterized for the strain used as type OXA whose pI was 7.1, with a molar mass of 49 kg/mol...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02877216
更新日期:1987-01-01 00:00:00
abstract::The morphology, host range, structural proteins and serological properties of Streptococcus thermophilus phages isolated from Finnish cheese plants were investigated. The results show that all the nine phages belong morphologically to Ackermann's group B1. The host-phage reactions and plating efficiency justify the di...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02883235
更新日期:1987-01-01 00:00:00
abstract::The kinetics of extracellular neutral proteinase synthesis by an isogenic stringent (IS58) and a relaxed (IS56) strain of B. subtilis were compared. The specific enzyme formation rate by the stringent strain was higher than that of the relaxed one. Norvaline addition (1 mg/mL) induced the formation of pppGpp and ppGpp...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02883234
更新日期:1987-01-01 00:00:00
abstract::Proteinase production by Lactobacillus murinus was influenced by temperature, glucose concentration, initial pH and nitrogen sources. Maximum proteinase production occurred at 45 degrees C, pH 6.6 and with 0.5% (W/V) glucose. Tryptone, peptone and gelatin inhibited it. ...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02877263
更新日期:1987-01-01 00:00:00
abstract::Patients suffering from periodontitis or periodontosis were selected for the study. Further subdivision of these groups was based on the presence or absence of herpes and/or adenoviruses in their oral lymphocytes and epithelial cells. The phagocytic and bactericidal activities of oral leukocytes isolated from the same...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02887577
更新日期:1987-01-01 00:00:00
abstract::Sporulation was repressed in the parent strain by various carbon sources whereas glucose-resistant mutants were resistant to them but not to glycerol 2-phosphate. Both mycobacillin and dipicolinic acid synthesis were repressed in the parent by some of the compounds tested, viz. glucose, pyruvate and glycerol 2-phospha...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02928000
更新日期:1986-01-01 00:00:00
abstract::The chloramphenicol resistance gene from pSa was introduced into T-DNA of pTi T37 of Agrobacterium tumefaciens by cointegration with intermediary plasmid based on pBR322. The resulting intermediary vector was mobilized to A. tumefaciens T37 by conjugative plasmid pRK2. The RK2 plasmid also forms contegrates with pTi d...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02926824
更新日期:1986-01-01 00:00:00
abstract::Dithiocarbamates were found to enhance the production of citric acid under solid-state fermentation conditions by Aspergillus niger. Maximum increase was observed with tetramethylthiuram disulfide (TMTD). Percent increases observed were 74.2% with 2.5 micrograms/mL of TMTD, 19.6% with 2.5 micrograms/mL of sodium dimet...
journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02926953
更新日期:1986-01-01 00:00:00